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MAJOR AND MINOR SURGICAL PROCEDURES ON PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS

JEROME M. GREENHOUSE, M.D.
AMA Arch Derm Syphilol. 1953;67(5):456-459. doi:10.1001/archderm.1953.01540050020003.
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THREE patients with systemic lupus erythematosus who required major operations have recently been observed. The decision to operate was given with some trepidation, in view of the reputed ill effects of surgical trauma in such cases. For example, textbooks state that it is dangerous to attack foci of infection by surgical methods, as this may cause an acute flare-up of lupus erythematosus, with possible death.1 Review of the literature revealed a difference of opinion as to whether surgical operations had any direct or indirect effect on patients suffering from this disease. Rothman and Felsher2 state: "Attempts to remove foci or alleged foci in subacute and acute cases have often ended with catastrophic results. The systemically ill lupus erythematodes patient cannot stand such procedures." Harold Orr3 states that "surgical interference of any sort should be avoided. The extraction of a tooth may cause a serious exacerbation, and so

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