Eczema Threatening Integrity of Skin Graft. Presented by Dr. George M. Lewis.
J. M., a boy aged 13, presented himself at the dermatology clinic of New York Hospital with dermatitis of the lower extremities of four months' duration. Three months prior to the appearance of the eruption the scar tissue of an old burn had been replaced by split-thickness grafts. He failed to respond to mild local medicaments and even became worse. All possible contact irritants were ruled out, and a biopsy was performed.
There is an erythematous, scaling, and exudative dermatitis confined to the site of the skin grafts.
Urinalysis showed no abnormalities, and the hemogram was within normal limits.
Biopsy showed the epidermis to be tremendously acanthotic with elongation of the rete pegs. Psoriasiform areas of parakeratosis were seen. Marked intracellular and intercellular edema was present. The granular layer was thin or absent. Numerous small vesicles were