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IS MYCOSIS FUNGOIDES A RETICULOENDOTHELIAL NEOPLASTIC ENTITY?

EDWARD P. CAWLEY, M.D.; ARTHUR C. CURTIS, M.D.; JAMES E. K. LEACH, M.D.
AMA Arch Derm Syphilol. 1951;64(3):255-272. doi:10.1001/archderm.1951.01570090002001.
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MYCOSIS fungoides was first described by Alibert (1812),1 who labeled the disease pian fungoide because some of the cutaneous lesions resembled those of yaws. Later (1835)2 he substituted the word "mycosis" for "pian" to describe the remarkable mushroom-like tumors but had no intention of suggesting that the disease was caused by fungi. In 1851, Bazin gave an admirable account of the clinical features of mycosis fungoides, and 13 years later Köbner described the disease as a "granuloma." Ranvier (1869) and Hebra (1872) were early contributors to knowledge of the histology of the disorder, and Auspitz (1885)3 first employed the term "granuloma fungoides." The striking d'emblée form of mycosis fungoides was recognized by Vidal and Brocq in 1885. Eight decades after Alibert's original contribution, Besnier and Hallopeau (1892)4 described the premycotic, erythematous stage of mycosis fungoides. In later years a great many investigators have been keenly interested

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