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LIQUID OXYGEN IN DERMATOLOGIC PRACTICE

ROY L. KILE, M.D.; ASHTON L. WELSH, M.D.
Arch Derm Syphilol. 1948;57(1):57-62. doi:10.1001/archderm.1948.01520130060004.
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LIQUID oxygen has been used by dermatologists since 1899,1 but it has received little attention since the introduction of solid carbon dioxide in dermatologic practice in 1907.2 In 1910, Gold3 described a method of making liquid oxygen and stated his impressions of the comparative use of it on cutaneous lesions with that of solid carbon dioxide. He expressed the opinion, as did Irvine and Turnacliff,4 that treatment with liquid oxygen caused much less pain than did treatment with solid carbon dioxide. All observed that the pain was much less if the freezing were confined to the lesions than if the adjacent tissue were also frozen. Irvine and Turnacliff4 reviewed the literature up to 1929 and related their experiences with the use of liquid oxygen. They were favorably impressed with the results which they obtained. In a discussion of this paper, Pusey stated that he conceived the

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