MANY reports from English and American investigators indicate that local applications of penicillin are useful in the treatment of pyogenic infections of the skin. Bodenham1 found that a penicillin cream was effective in eliminating streptococci and staphylococci from burns and surface wounds. Roxburgh, Christie and Roxburgh2 prepared a penicillin ointment and a penicillin spray. They reported that local applications of penicillin were effective in the treatment of sycosis barbae and impetigo. Taylor and Hughes3 applied penicillin ointment and penicillin in a spray to lesions of impetigo, sycosis barbae and furunculosis, with favorable results. Sophian and Connolly4 treated acute and chronic pyogenic infections of the skin with a penicillin ointment containing a wetting agent. The results were good, especially in furunculosis and sycosis barbae. Schoch5 applied the washings of "empty" penicillin ampules to the lesions of 4 patients with diseases of the skin and was enthusiastic as to the
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