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EPIDERMAL AND DERMAL HYPERSENSITIVITY IN PATIENTS WITH FUNCTIONAL DERMATOSES:  AS DEMONSTRATED BY PATCH AND SCRATCH TESTS

M. E. OBERMAYER, M.D.; S. WILLIAM BECKER, M.D.; LOUIS LLOYD PRAVER, M.D.; CLARENCE SHAW, M.D.; FREDERIC BECKER, M.D.
Arch Derm Syphilol. 1936;34(3):411-420. doi:10.1001/archderm.1936.01470150061005.
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This report represents the result of a study which was undertaken as a part of a comprehensive investigation of patients with neurodermatoses, of which two other parts1 have been published.

In order to be able to compare the results with those obtained by others, we used the same technic and the same choice of materials throughout as were employed by Peck and Salomon.2

A number of chronic recurrent dermatoses of hitherto obscure origin have been the subject of controversy during the last one or two decades. The conditions in question are considered "functional," since no organic background can be detected. From this point trends of thought diverge. One group contends that the diseases are allergic; the other maintains that there is an underlying nonspecific protoplasmic instability (neurocirculatory instability of Becker) which is considered prerequisite for an engrafted allergic disease. This study was undertaken for the purpose

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