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THE ANNULAR MACULAR SYPHILID (NEUROSYPHILID, UNNA)

FRANK C. COMBES, M.D.
Arch Derm Syphilol. 1932;25(5):906-914. doi:10.1001/archderm.1932.01450020932015.
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The annular macular syphilid, or the neurosyphilid of Unna, is one of the rarer manifestations of syphilis, and, oddly, one that is alluded to in only a few of the textbooks on dermatologic practice. The first case to be presented before a dermatologic society in this country was by Howard Fox1 in 1917. The case herein presented agreed in its various manifestations with those previously described, but showed also some unusual lesions of the genitals.

Insufficient treatment for early syphilis is responsible for the reappearance of secondary cutaneous symptoms. These relapsing roseolas may recur several times during the first few years of the disease. Harttung2 mentioned one patient, treated with mercury, in whom the syphilid recurred five times in three years, disappearing after each recurrence. Fournier3 reported a case in which a relapse occurred eight times in four years.

The purpose of this communication is to

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