A careful review of the literature revealed fourteen instances of xanthomas involving members of the same family. This number comprised a total of forty-two patients. It is permissible, therefore, to class cases of familial xanthomas among the rarities and add them to the cases previously recorded.
Attention was first called to familial cases of xanthoma, in 1889, by Ehrmann,1 and Lehzen and Knauss.2 Ehrmann's cases occurred in two brothers, aged 7 and 9 years, respectively. In both, the eruption began when the brothers were aged 5 years, and was present over the elbows and buttocks.
Lehzen and Knauss reported the case of a girl, aged 11 years, who presented both xanthomas and xanthelasmas. The eruption first made its appearance when the patient was 4 years of age. Her sister, aged 9 years, presented an identical eruption, which made its appearance when she was 3 years old. The older