In 1927, Kreibich reported a case of what he called granuloma senilis, in which the following history was given.
A woman, aged 55, had had about fifty typical warts on her back for many years. During the last three months, two of them had ulcerated and appeared as red nodular elevations, one as large as a hazelnut, the other the size of a pigeon's egg. After removal of a brown crust, an irregular papillomatous surface was seen which on one edge was continuous with a senile wart. It was diagnosed as carcinoma of a senile wart and was excised. Histologically, there was a definite epithelial margin of basal cells. With the exception of the superficial ulceration and edema of the rete pegs, the section was similar to that of the adjacent senile warts. In calling this lesion a granuloma senilis, Kreibich pointed out that the name indicates a granuloma of