Twenty-five years ago, I wrote an essay on hematogenous infections and toxic dermatoses. In this paper, I critically summed up the existing knowledge in the light of my own experience. Today I shall again attempt such a summary, but only as far as it is possible to do so in a lecture; that is, only on general lines, and almost entirely restricting myself to infectious processes, to newer facts and to experiences in my own clinic.
At the time of my first paper, I defined hematogenous dermatoses as "Those diseases in which the agent causing the disease is brought, by the blood, directly into the skin and there causes its corresponding manifestations." I should not yet care to change anything in this definition.
I defined as toxic those dermatoses in which substances in solution affect the skin, without it being demonstrable that these substances are deposited there (conditions produced by