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July 1926, Vol 14, No. 1 >
Article | July 1926

THE FOX-FORDYCE SYNDROME

HERMAN GOODMAN, B.S., M.D.
Arch Derm Syphilol. 1926;14(1):46-49. doi:10.1001/archderm.1926.02370190059007.
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ABSTRACT

HISTORY  The clinical and histologic reports of this disease, which received the eponym of Fox-Fordyce disease, were published in 1902. The title of the contribution was "Two Cases of a Rare Papular Disease Affecting the Axillary Region." Fox gave the particulars regarding a woman patient who presented an intensely itching eruption confined mainly to the axillary regions, which had been present a year or more. The patient was thin and neurotic. The lesions were smooth, papular, numerous, firm and rounded. The skin was deeply infiltrated and slightly fissured. The color was normal. Treatment of the ordinary kind was fruitless. After eleven months in the hospital, the patient was discharged unimproved.Fox briefly mentioned one other patient, but no other details are given than these: This occurred in a young man who was extremely neurotic, and who suffered much from the intense pruritus. As in the case reported above, the eruption

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