0
Editorial |

A Fresh Look at Incontinentia Pigmenti

Rudolf Happle, MD
Arch Dermatol. 2003;139(9):1206-1208. doi:10.1001/archderm.139.9.1206.
Text Size: A A A
Published online

Extract

THE CLINICAL and genetic particularities of incontinentia pigmenti (IP) have attracted the attention of many authors since the X-linked dominant, male-lethal transmission of this trait was discovered.1 Lately, the advances of molecular research have yielded fascinating new insights into this disorder.2,3 As a provocative counterpart, Hadj-Rabia and colleagues4 present in this issue an almost exclusively clinical study elaborated in a rather traditional way. Although, in most of cases, the diagnosis was not confirmed by molecular analysis, the authors show that even today working in this manner can provide worthwhile information. Yet, all of the data regarding the frequency of associated anomalies should be taken with great caution because this is a retrospective study. The neonates with a diagnostic label of "incontinentia pigmenti" were not routinely seen by a dermatologist. Rather, the relevant information was obtained by reviewing the medical records of 43 girls and 4 boys referred to a children's hospital in Paris from 1986 through 1999. The authors come to the conclusion that the diagnosis was correct in only 40 cases.

Topics

Sign In to Access Full Content

Don't have Access?

Register and get free email Table of Contents alerts, saved searches, PowerPoint downloads, CME quizzes, and more

Subscribe for full-text access to content from 1998 forward and a host of useful features

Activate your current subscription (AMA members and current subscribers)

Purchase Online Access to this article for 24 hours

First Page Preview

View Large
/>
First page PDF preview

Figures

Tables

References

Correspondence

CME
Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).
Submit a Comment

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Web of Science® Times Cited: 4

Sign In to Access Full Content

Related Content

Customize your page view by dragging & repositioning the boxes below.

See Also...
Jobs
brightcove.createExperiences();