About This Journal FREE

The Archives of Dermatology publishes information concerning the skin, its diseases, and their treatment. Its mission is to explicate the structure and function of the skin and its diseases and the art of using this information to deliver optimal medical and surgical care to the patient. We attempt to enhance the understanding of cutaneous pathophysiology and improve the clinician's ability to diagnose and treat skin disorders. This journal has a particular interest in publishing clinical and laboratory studies that reveal new information pertinent to the interests and needs of the medical dermatologist, dermatologic surgeon, and all those concerned with state-of-the-art care of cutaneous disease. We believe that knowledge derived from well-designed clinical trials and studies of cost-effectiveness are especially important for improving the practice of dermatology. Studies that increase the understanding of the outcome of treatment or the means by which the burden of dermatologic disease can be measured and reduced to promote the health of patients with skin disease will receive special priority. The ARCHIVES regularly publishes reports on clinical investigations, editorials, and reviews. It also features reports and discussions on clinicopathologic correlations; clinical disorders of unique didactic value; pharmacologic, medical and surgical therapeutics; and ethical, moral, socioeconomic, and political issues.

Kenneth A. Arndt, MD

Robin L. Travers, MD

Michael S. Kaminer, MD

Linda S. Wong, Sandra M. Yong

1244 Boylston St, Suite 305 Chestnut Hill, MA 02467 (617) 232-2344 Fax (617) 232-1945 e-mail: archderm@aol.com

Archives a Century Ago: Mark Bernhardt, MD, Ft Lauderdale, Fla Book and New Media Reviews: Murad Alam, MD, Chicago, Ill Critical Situations: Anita G. Licata, MD, St Louis, Mo The Cutting Edge: George J. Hruza, MD, St Louis, Mo Assistant Section Editors: Dee Anna Glaser, MD, St Louis, Mo  Elaine Siegfried, MD, St Louis, Mo Evidence-Based Dermatology: Michael Bigby, MD Rosamaria Corona, DSc, MD Damiano Abeni, MD, MPH Paolo Pasquini, MD, MPH Moyses Szklo, MD, MPH, DrPh Hywel Williams, MSc, PhD, FRCP The Art and the Calling: David J. Elpern, MD, Williamstown, Mass Luminaire: Ponciano D. Cruz, Jr, MD, Dallas Tex  Jennifer Aranda, MD, Dallas, Tex Off-Center Fold: Michael E. Ming, MD, Philadelphia, Pa On the Horizon: Gary S. Wood, MD, Madison, Wis Web Editor: Harvey Lui, MD, FRCPC, Vancouver, British Columbia CME Editor: Andrew D. Samel, MD, Attleboro, Mass

Michael Bigby, MD, Boston, Mass Mary-Margaret Chren, MD, San Francisco, Calif Ponciano D. Cruz, Jr, MD, Dallas, Tex Irene E. Edwards, MD, Charlotte, NC David J. Elpern, MD, Williamstown, Mass Alan B. Fleischer, Jr, MD, Winston-Salem, NC Ilona J. Frieden, MD, San Francisco, Calif Richard G. Glogau, MD, San Francisco, Calif George J. Hruza, MD, St Louis, Mo Timothy M. Johnson, MD, Ann Arbor, Mich Arnold W. Klein, MD, Beverly Hills, Calif David J. Leffell, MD, New Haven, Conn Harvey Lui, MD, FRCPC, Vancouver, British Columbia David J. Margolis, MD, PhD, Philadelphia, Pa Michael E. Ming, MD, Philadelphia, Pa Seth J. Orlow, MD, PhD, New York, NY Gary S. Wood, MD, Madison, Wis

Alvaro E. Acosta, MD, Bogota, Colombia Jan Nico Bouwes Bavinck, MD, Leiden, the Netherlands Reuven Bergman, MD, Haifa, Israel Francisco G. Bravo, MD, Lima, Peru Francisco Camacho-Martinez, MD, Seville, Spain Lorenzo Cerroni, MD, Graz, Austria Roberto Cortes-Franco, MD, Mexico City, Mexico Yahya Dowlati, MD, PhD, Tehran, Iran Reinhard Drummer, MD, Zurich, Switzerland Odile Enjolras, MD, Paris, France James Ferguson, MD, Dundee, Scotland Miguel Ruben Guarda, MD, Santiago, Chile John L. M. Hawk, MD, London, England Jana Hercogova, MD, Prague, Czech Republic Chung-Hong Hu, MD, FACP, Taipei, Taiwan Abdul-Ghani M. Kibbi, FACP, MD, Beirut, Lebanon Steven Kossard, MD, Sydney, Australia Margarita M. Larralde, MD, Buenos Aires, Argentina Sungnack Lee, MD, Suwon, Korea Thomas A. Luger, MD, Munster, Germany Gillian Murphy, MD, Dublin, Ireland Oumeish Y. Oumeish, MD, Amman, Jordan Niwat Polnikorn, MD, FRCP(T), Bangkok, Thailand Marcia Ramos-e-Silva, MD, PhD, Rio de Janeiro, Brazil Hiroshi Shimizu, MD, Sapporo, Japan Mohsen Soliman, MD, Cairo, Egypt John D. Stratigos, MD, Athens, Greece T. Thirumoorthy, MD, Singapore Antonella Tosti, MD, Bologna, Italy Hans Christian Wulf, MD, Copenhagen, Denmark Wen-Yuan Zhu, MD, Nanjing, China

David J. Leffell, MD, Chairman Leslie Baumann, MDMarc D. Brown, MDJeffrey S. Dover, MD FRCPScott W. Fosko, MDGlenn D. Goldman, MDRoy C. Grekin, MDWilliam Hanke, MDTimothy M. Johnson, MDArielle N. B. Kauvar, MDArnold W. Klein, MDBarry Leshin, MDSeth L. Matarasso, MDS. Teri McGillis, MDNeil S. Sadick, MD

Offices: 515 N State St, Chicago, IL 60610

Catherine D. DeAngelis, MD, MPH  Editor in Chief, Scientific Publications & Multimedia Applications

Cheryl Iverson Managing Editor

Department Director: Paula Glitman Copyediting Manager: Gwen Chaffen Freelance Copyediting Manager: Diane L. Cannon Freelance Copyediting Coordinators: Lauren B. Fischer, Connie Manno Editorial Systems Managers: Paul Frank, Monica Mungle Systems Programmer/Internet Specialist: J. D. Neff Senior Copy Editors: Dee E. Egger, Vickey Golden, John McFadden Copy Editors: Elisabeth Caron, Donald S. Smith Editorial Assistant: Wanda Hill

Assistant to the Editor: Marla A. Hall

Director: Margaret Winker, MD Electronic Media Department Director: Michelle Kurzynski Associate Web Editors: Katherine Behar, Erin M. Giannini Web Office Manager: Nadine Siewnarine

Group Publisher: Nawin Gupta, PhD VP Office Staff: James Clinton, Geoffrey Flick, Terri Hanley, Maureen Archey, Anna Goins International Business and Development: William Fox (director), Norman Frankel, PhD, Rhonda Bailey, Millette Jackson-Bates Online Business and CME: Bonnie Chi-Lum, MD, MPH (publisher)

Director: Curt Reilly Managers: Vida Damijonaitis, Kim Krebs, Thalia Moss Staff: Kathy Braun, Ana Dirksen, Sandra Garzon, Christine Hearne, Amy Postlewait, Trina Rizzo, Barbara Van Wagner

Director: Peter J. Murphy Sales Representative: Alexis A. O'Connell Marketing Services: Nancy Bell Staff: Victoria Anne Acot, Susan Lovenberg, Mirna Monal, Debra Ann Sardo

Director: Mark Kuhns Staff: Wanda Bartolotta, Joseph Rekash

Division Director: Vanessa Hayden Directors: Karen Adams-Taylor, Paul Gasiecki, Sue Sherrill Managers: David Antos, Karen Branham, Debbie Camp, Diane Darnell, Karl Elvin, Betty Frigerio, Linda Gardner, Mary Ellen Johnston, Mark Matura, Michael McGraw, Phil O'Leary, Susan Price, Charl Richey, Alfred Tomaselli, Carmela Ware Advertising and Production Services: Linda Alexander, LaWanda Brown, Susan Chiara, Mary Anne Donley, Euwanaha Joiner-Smith, Brian McCartney, Sean O'Donnell, Noemi Olmo, Carole Piszker, Sarah Powell, Denise Steinhauser, Ellen Yoshihara Circulation Processing: Bernadette Bauer, Julie Burton, Rosa Eng, Felicia Kyles, Lawrence Majkszak, Kathryn Osten Composition and New Media: Rebecca Aiken, Clifford Barrett, Gail Barrett, Regina Brownlee, Brenda Chandler-Grayer, Rowena Dagang, Amy Evers, Mary Ann Kuranda, Sandra Lopez, John Marcinek, Bruce McGregor, La'son Diggs Sledge, Angela Smits Graphics: Joe Amft, Fred Furtner, Carolyn Hall, Maria Kowalkowski, Chris Meyer, JoAnne Weiskopf Proofreading: Carol Joy Farrell, Daniel James, Judith A. Literskis, Teresa H. Omiotek, Barbara Wojtowicz, Agnes A. Zarkadas

Michael D. Maves, MD, MBA, Executive Vice President, Chief Executive Officer Robert A. Musacchio, PhD, Senior Vice President, Publishing & Business Services

All articles published, including editorials, letters, and book reviews, represent the opinions of the authors and do not reflect the policy of the American Medical Association, the Editorial Board, or the institution with which the author is affiliated, unless this is clearly specified.

Copyright 2003 by the American Medical Association. All rights reserved. Reproduction without permission is prohibited.