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Follicular Toxic Effects of Chimeric Anti–Epidermal Growth Factor Receptor Antibody Cetuximab Used to Treat Human Solid Tumors

Arash Kimyai-Asadi, MD; Ming H. Jih, MD, PhD
Arch Dermatol. 2002;138(1):129-131. doi:10.1001/archderm.138.1.125.
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Waksal  HW Role of an anti–epidermal growth factor receptor in treating cancer. Cancer Metastasis Rev. 1999;18427- 436
Mendelsohn  JShin  DMDonato  N  et al.  A phase I study of chimerized anti–epidermal growth factor receptor (EGFr) monoclonal antibody, C225, in combination with cisplatin (CDDP) in patients (pts) with recurrent head and neck squamous cell carcinoma (SCC).  Program and abstracts of the 35th Annual Meeting of the American Society of Clinical Oncology May 15-18, 1999 Atlanta, GaAbstract 1502
Baselga  JPfister  DCooper  MR  et al.  Phase I studies of anti–epidermal growth factor receptor chimeric antibody C225 alone and in combination with cisplatin. J Clin Oncol. 2000;18904- 914
Ezekiel  MPBonner  JARobert  F  et al.  Phase I trial of chimerized anti–epidermal growth factor receptor (Anti-EGFr) antibody in combination with either once-daily or twice-daily irradiation for locally advanced head and neck malignancies.  Program and abstracts of the 35th Annual Meeting of the American Society of Clinical Oncology May 15-18, 1999 Atlanta, GaAbstract 1501
Murillas  RLarcher  FConti  CJSantos  MUllrich  AJorcano  JL Expression of a dominant negative mutant of epidermal growth factor receptor in the epidermis of transgenic mice elicits striking alterations in hair follicle development and skin structure. EMBO J. 1995;145216- 5223
Hansen  LAAlexander  NHogan  ME  et al.  Genetically null mice reveal a central role for epidermal growth factor receptor in the differentiation of the hair follicle and normal hair development. Am J Pathol. 1997;1501959- 1975
Guy  RGreen  MRKealey  T Modeling acne in vitro. J Invest Dermatol. 1996;106176- 182
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