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The Cutting Edge: Challenges in Medical and Surgical Therapies |

Narrowband UV-B Phototherapy for the Treatment of Acne Vulgaris During Pregnancy

Joshua A. Zeichner, MD
Arch Dermatol. 2011;147(5):537-539. doi:10.1001/archdermatol.2011.96.
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Extract

The treatment of acne during pregnancy is a challenge because of the potential teratogenic effects. Medications currently deemed safe during pregnancy are largely unsatisfactory in treating acne. Narrowband (NB) UV-B phototherapy is a safe option for treatment of psoriasis during pregnancy. We report the successful use of NB UV-B for the treatment of acne in a pregnant patient.

REFERENCES
Sannerstedt  RLundborg  PDanielsson  BR  et al.  Drugs during pregnancy: an issue of risk classification and information to prescribers. Drug Saf 1996;14 (2) 69- 77
PubMed
Hale  EKPomeranz  MK Dermatologic agents during pregnancy and lactation: an update and clinical review. Int J Dermatol 2002;41 (4) 197- 203
PubMed
Meffert  HGaunitz  KGutewort  TAmlong  UJ Therapy of acne with visible light: decreased irradiation time by using a blue-light high-energy lamp. Dermatol Monatsschr 1990;176 (10) 597- 603
PubMed
Karu  TIKolyakov  SF Exact action spectra for cellular responses relevant to phototherapy. Photomed Laser Surg 2005;23 (4) 355- 361
PubMed
Gold  MH Acne vulgaris: lasers, light sources and photodynamic therapy: an update 2007. Expert Rev Anti Infect Ther 2007;5 (6) 1059- 1069
PubMed
Webster  GF Light and laser therapy for acne: sham or science? facts and controversies. Clin Dermatol 2010;28 (1) 31- 33
PubMed
Cunliffe  WJ Acne. 
Hjorth  NSjolin  KESylvest  BThomsen  K Acne aestivalis: Mallorca acne. Acta Derm Venereol 1972;52 (1) 61- 63
PubMed
Menter  AKorman  NJElmets  CA  et al.  Guidelines of care for the management of psoriasis and psoriatic arthritis, section 5: guidelines of care for the treatment of psoriasis with phototherapy and photochemotherapy. J Am Acad Dermatol 2010;62 (1) 114- 135
PubMed
Sethi  GSodhi  A Role of p38 mitogen-activated protein kinase and caspases in UV-B-induced apoptosis of murine peritoneal macrophages. Photochem Photobiol 2004;79 (1) 48- 54
PubMed
Walters  IBBurack  LHCoven  TRGilleaudeau  PKrueger  JG Suberythemogenic narrow-band UVB is markedly more effective than conventional UVB in treatment of psoriasis vulgaris. J Am Acad Dermatol 1999;40 (6, pt 1) 893- 900
PubMed
Tauscher  AEFleischer  AB  JrPhelps  KCFeldman  SR Psoriasis and pregnancy. J Cutan Med Surg 2002;6 (6) 561- 570
PubMed
Vun  YYJones  BAl-Mudhaffer  MEgan  C Generalized pustular psoriasis of pregnancy treated with narrowband UVB and topical steroids. J Am Acad Dermatol 2006;54 (2) ((suppl)) S28- S30
PubMed
Ingham  EEady  EAGoodwin  CECove  JHCunliffe  WJ Pro-inflammatory levels of interleukin-1 alpha-like bioactivity are present in the majority of open comedones in acne vulgaris. J Invest Dermatol 1992;98 (6) 895- 901
PubMed
Suh  DHKwon  TEYoun  JI Changes of comedonal cytokines and sebum secretion after UV irradiation in acne patients. Eur J Dermatol 2002;12 (2) 139- 144
PubMed
Fluhr  JWGloor  M The antimicrobial effect of narrow-band UVB (313 nm) and UVA1 (345-440 nm) radiation in vitro. Photodermatol Photoimmunol Photomed 1997;13 (5-6) 197- 201
PubMed
Lesnik  RHKligman  LHKligman  AM Agents that cause enlargement of sebaceous glands in hairless mice, II: ultraviolet radiation. Arch Dermatol Res 1992;284 (2) 106- 108
PubMed
Akitomo  YAkamatsu  HOkano  YMasaki  HHorio  T Effects of UV irradiation on the sebaceous gland and sebum secretion in hamsters. J Dermatol Sci 2003;31 (2) 151- 159
PubMed
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Figures

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Figure 1.

Inflammatory papules and pustules on the face and neck in a woman who was 5 months pregnant.

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Figure 2.

Improvement in inflammatory lesions after 2 months of narrowband UV-B treatments 3 times a week.

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