Epidermolysis bullosa acquisita (EBA) is a rare, chronic, autoimmune bullous dermatosis caused by autoantibodies against type VII collagen. In this case report, Abrams et al describe a neonate with transient neonatal EBA due to the passive transfer of maternal autoantibodies. The infant's mother had been diagnosed as having EBA 1 year before the infant was born. She had discontinued immunosuppressive therapy during her first trimester of pregnancy. Her daughter was born with multiple superficial and deep erosions on the face, chest, abdomen, and extremities, and histopathologic analysis, immunofluorescence studies, and enzyme-linked immunosorbent assay (ELISA) confirmed the diagnosis. With the expectation of spontaneous tapering in circulating antibody levels, immunosuppressive therapies were withheld in favor of supportive treatments. At age 2 months, all erosions were healed.