Extensive laboratory evaluations were performed. Abnormalities were found in values for monocytes, neutrophils, erythrocyte sedimentation rate, hemoglobin, glucose, rheumatoid factor, and antinuclear antibody. All other results were negative or normal (Table 1), including calcium; angiotensin-converting enzyme; aldolase; cyclic citrullinated peptide; immunoglobulins A, M, D, total IgG, IgG2, IgG3, and IgG4; antibodies to myeloperoxidase, proteinase 3, double-stranded DNA, and extractable nuclear antigens (SS-A, SS-B, RNP, Sm, Jo-1, and Scl-70); tuberculin skin test; serum protein electrophoresis; and urinalysis. Peripheral blood flow cytometric immunophenotyping revealed no clonal B- or T-lymphocyte abnormality and no quantitative subset abnormality. The results of peripheral blood T-cell receptor gene rearrangement analysis were negative. Computed tomograms of the chest, abdomen, and pelvis demonstrated mediastinal and abdominal adenopathy (without evidence of hilar or paratracheal adenopathy) and borderline splenomegaly.