We're unable to sign you in at this time. Please try again in a few minutes.
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Editorial |

Cutaneous Signs of Hematologic Malignancies “Doctor, Is There Something Wrong With My Blood?”

Jose M. Mascaró Jr, MD
Arch Dermatol. 2011;147(3):342-344. doi:10.1001/archdermatol.2011.25.
Text Size: A A A
Published online


As dermatologists who are constantly faced with different types of cutaneous lesions and disorders, we find that it is not uncommon that patients ask about the possible cause or origin of these eruptions. Many patients believe that all the macules, papules, urticaria, or nodules that have appeared on their skin are due to an as-yet undiscovered allergy. In other cases, patients or their companions fear that these eruptions appear because of an internal disease, mostly a “blood disease.” Thus, once we have examined their skin thoroughly, it is not uncommon to hear from them: “Doctor, is there something wrong with my blood?” (In Spanish: “ Doctor, ¿no será que tengo algo en la sangre? ”). Luckily, most of the times we can readily reassure them that their skin is the only place where something is going wrong, for most of these eruptions are common skin diseases, such as urticaria, psoriasis, eczema, and so forth.

Figures in this Article

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

First Page Preview

View Large
First page PDF preview


Place holder to copy figure label and caption
Figure 1

Pyoderma gangrenosum on the leg of a 79-year-old woman with an associated IgA monoclonal gammopathy.

Graphic Jump Location
Place holder to copy figure label and caption
Figure 2

Exaggerated insect bite reaction, which is also called “eosinophilic dermatosis of myeloproliferative disease,” on the arm of a 52-year-old woman with chronic lymphocytic leukemia. The patient presented with recurrent episodes of swelling, erythema, and tense blisters on her face, trunk, and limbs.

Graphic Jump Location




Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.


Some tools below are only available to our subscribers or users with an online account.

1 Citations

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

Related Content

Customize your page view by dragging & repositioning the boxes below.

See Also...
Articles Related By Topic
Related Collections
PubMed Articles