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Correspondence |

Dilute Bleach Baths for Staphylococcus aureus Colonization in Atopic Dermatitis to Decrease Disease Severity

Jennifer T. Huang, MD; Alfred Rademaker, PhD; Amy S. Paller, MD
Arch Dermatol. 2011;147(2):246-247. doi:10.1001/archdermatol.2010.434.
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A commentary published recently in the Archives1 addressed some omissions in methods and raised some questions about our group's recent article2 describing the value of dilute sodium hypochlorite baths and intranasal mupirocin for moderate to severe atopic dermatitis in infection-prone patients. We are writing to provide clarification.

The study was a single-blind, randomized investigation using permuted blocks of size 4. All investigators were blinded to the randomization schedule, and they assigned the appropriately numbered ointment and “bleach” to subjects. Data were analyzed by intent to treat, with analysis grouped by treatment randomized to, rather than by, treatment received.

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