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February 2011February 21, 2011, Vol 147, No. 2 >

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The Cutting Edge: Challenges in Medical and Surgical Therapies | February 2011February 21, 2011

Retiform Purpura and Digital Gangrene Secondary to Antiphospholipid Syndrome Successfully Treated With Sildenafil

Mercedes E. Gonzalez, MD; Philip Kahn, MD; Harper N. Price, MD; Hideko Kamino, MD; Julie V. Schaffer, MD
Arch Dermatol. 2011;147(2):164-167. doi:10.1001/archdermatol.2011.4.
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REFERENCES
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Figure 1

Clinical photographs of hemorrhagic bulla and retiform purpura. A, Hemorrhagic bulla on the distal left first toe and necrotic ulcer with loss of the nail on the second toe. B, Retiform purpura on the left first and second toes, and dusky reticular erythema on the third and fourth toes.

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Figure 2

Fibrin thrombi in the lumens of small and medium-sized blood vessels throughout the mid and deep reticular dermis, with partial necrosis of eccrine glands and the overlying epidermis. A, Hematoxylin-eosin, original magnification ×10; B, hematoxylin-eosin, original magnification ×40.

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Figure 3

Three months after presentation, the patient had lost only the second toenail (A) and a small amount of tissue from the tips of her first and second toes (B).

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