Correspondence |

Acneiform Follicular Mucinosis Responding to Hydroxychloroquine

Forrest N. White, BS; Paul R. Bergstresser, MD; Darci Lamontagne, RN, CPNP; J. Scott Boswell, MD
Arch Dermatol. 2010;147(1):130-131. doi:10.1001/archdermatol.2010.405.
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Follicular mucinosis (FM) is an uncommon dermatologic disorder in which mucin accumulates in hair follicles, leading to follicular degeneration and hair loss. Clinically, it usually presents as follicular papules or indurated, erythematous plaques, most commonly on the head and neck. Less common manifestations include lesions resembling alopecia areata, scarring alopecia, nodules, cysts, eczema, and chronic acneiform eruptions.1,2 Herein we report a pediatric case of acneiform FM that showed an excellent response to hydroxychloroquine.

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Figure 1.

Clinical presentation before (A) and after (B) 4 weeks of hydroxychloroquine therapy.

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Figure 2.

Histologic presentations showing mucin deposition within and around hair follicles. A, Hematoxylin-eosin, original magnification ×400; B, colloidal iron, original magnification ×100.

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