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Correspondence |

Clear Cell Papulosis of the Skin: Acquired Hypomelanosis

Ji Hyun Sim, MD; Jeung Eun Do, MD; You Chan Kim, MD, PhD
Arch Dermatol. 2011;147(1):128-129. doi:10.1001/archdermatol.2010.382.
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Kuo  TTChan  HLHsueh  S Clear cell papulosis of the skin: a new entity with histogenetic implications for cutaneous Paget's disease. Am J Surg Pathol 1987;11 (11) 827- 834
PubMed Link to Article[[XSLOpenURL/10.1097/00000478-198711000-00001]]
Yu  YSukhatme  SLoo  DS Clear cell papulosis: a connection of clear cells to toker cells or paget disease. Arch Dermatol 2009;145 (9) 1066- 1068
Benouni  SKos  LRuggeri  SYNorth  PEDrolet  BA Clear cell papulosis in Hispanic siblings. Arch Dermatol 2007;143 (3) 358- 360
Mohanty  SKArora  RKakkar  NKumar  B Clear cell papulosis of the skin. Ann Diagn Pathol 2002;6 (6) 385- 388
PubMed Link to Article[[XSLOpenURL/10.1053/adpa.2002.36653]]
Lee  JYChao  SC Clear cell papulosis of the skin. Br J Dermatol 1998;138 (4) 678- 683
PubMed Link to Article[[XSLOpenURL/10.1046/j.1365-2133.1998.02185.x]]
Kumarasinghe  SPChin  GYKumarasinghe  MP Clear cell papulosis of the skin: a case report from Singapore. Arch Pathol Lab Med 2004;128 (11) e149- e152
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Figure 1.

Multiple, grouped, oval to round, hypopigmented macules and minimally palpable flat-topped papules in the suprapubic area; the inset shows a close-up of the hypopigmented lesion.

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Figure 2.

Histopathologic findings. A, Scattered enlarged clear cells within the basal and occasionally the spinous layers (hematoxylin-eosin; original magnification ×400). B, The clear cells show immunoreactivity to carcinoembryonic antigen (original magnification ×400). Decreased pigmentation is seen in the skin lesions (C) compared with normal skin (D) (Fontana-Masson stain, original magnification ×200).

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