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The Cutting Edge: Challenges in Medical and Surgical Therapies |

Efficacy of Intravenous Cidofovir in the Treatment of Giant Molluscum Contagiosum in a Patient With Human Immunodeficiency Virus

Corinne Erickson, MD; Marcia Driscoll, MD; Anthony Gaspari, MD
Arch Dermatol. 2011;147(6):652-654. doi:10.1001/archdermatol.2011.20.
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Molluscum contagiosum virus (MCV) is a DNA virus in the Poxviridae family that may cause extensive and voluminous lesions often resistant to topical therapies in patients with AIDS and other immunocompromised patients. We present a case of eruptive giant molluscum that caused remarkable deformity in a patient with AIDS. Intravenous (IV) cidofovir was used as therapy, resulting in dramatic improvement.

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Patient before (A), during (B), and after (C) intravenous cidofovir treatment course.

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