Correspondence |

Pigmented Basal Cell Carcinomas 15 Years After Orbital Radiation Therapy for Graves Ophthalmopathy

Holger A. Haenssle, MD; Arne Richter, MD; Timo Buhl, MD; Ellen Haas, MD; Ricarda Holzkamp, MD; Steffen Emmert, MD; Michael P. Schön, MD
Arch Dermatol. 2011;147(4):511-512. doi:10.1001/archdermatol.2011.74.
Text Size: A A A
Published online


Menzies  SWWesterhoff  KRabinovitz  HKopf  AW McCarthy  WHKatz  B Surface microscopy of pigmented basal cell carcinoma. Arch Dermatol 2000;136 (8) 1012- 101610926737
Ron  EModan  BPreston  DAlfandary  EStovall  MBoice  JD  Jr Radiation-induced skin carcinomas of the head and neck. Radiat Res 1991;125 (3) 318- 3252000456
Ron  E Cancer risks from medical radiation. Health Phys 2003;85 (1) 47- 5912852471
Stiebel-Kalish  HRobenshtok  EHasanreisoglu  MEzrachi  DShimon  ILeibovici  L Treatment modalities for Graves' ophthalmopathy: systematic review and metaanalysis. J Clin Endocrinol Metab 2009;94 (8) 2708- 271619491222
Evans  DGLadusans  EJRimmer  SBurnell  LDThakker  NFarndon  PA Complications of the naevoid basal cell carcinoma syndrome: results of a population based study. J Med Genet 1993;30 (6) 460- 4648326488
Figures in this Article

Sign In to Access Full Content

Don't have Access?

Register and get free email Table of Contents alerts, saved searches, PowerPoint downloads, CME quizzes, and more

Subscribe for full-text access to content from 1998 forward and a host of useful features

Activate your current subscription (AMA members and current subscribers)

Purchase Online Access to this article for 24 hours

First Page Preview

View Large
First page PDF preview


Place holder to copy figure label and caption
Figure 1.

Pigmented bilateral basal cell carcinoma (BCC) of the temple. A and B, Right (A) and left (B) hair-covered temples after shaving. C and D, Asymmetric gray-brown tumor with a few scales (C) and asymmetric trabecular tumor of gray-brown color and central ulceration (D) (white frames indicate field of view for dermoscopy, and scale bars indicate centimeters). E and F, Dermoscopy of the right (E) and left (F) temple BCCs reveal spoke wheel areas (boxes 1), blue-gray ovoid nests (boxes 2), arborizing vessels (box 3), and central ulceration (box 4) (original magnifications ×50 [E] and ×20 [F]).

Graphic Jump Location
Place holder to copy figure label and caption
Figure 2.

Histopathologic analysis of the excised tumors. Nests of basaloid cells with palisading nuclei are seen in the periphery surrounded by fibromyxoid stroma and lymphocytic infiltrates. Prominent pigment particles account for the macroscopically evident hyperpigmentation of the tumors (hematoxylin-eosin, original magnification ×40).

Graphic Jump Location




Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).
Submit a Comment


Some tools below are only available to our subscribers or users with an online account.

Sign In to Access Full Content

Related Content

Customize your page view by dragging & repositioning the boxes below.

Articles Related By Topic
Related Topics
PubMed Articles

The Rational Clinical Examination
Evidence Summary and Review 3