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Correspondence |

Pigmented Basal Cell Carcinomas 15 Years After Orbital Radiation Therapy for Graves Ophthalmopathy

Holger A. Haenssle, MD; Arne Richter, MD; Timo Buhl, MD; Ellen Haas, MD; Ricarda Holzkamp, MD; Steffen Emmert, MD; Michael P. Schön, MD
Arch Dermatol. 2011;147(4):511-512. doi:10.1001/archdermatol.2011.74.
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Menzies  SWWesterhoff  KRabinovitz  HKopf  AW McCarthy  WHKatz  B Surface microscopy of pigmented basal cell carcinoma. Arch Dermatol 2000;136 (8) 1012- 101610926737
Link to Article[[XSLOpenURL/10.1001/archderm.136.8.1012]]
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Link to Article[[XSLOpenURL/10.2307/3578117]]
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Link to Article[[XSLOpenURL/10.1097/00004032-200307000-00011]]
Stiebel-Kalish  HRobenshtok  EHasanreisoglu  MEzrachi  DShimon  ILeibovici  L Treatment modalities for Graves' ophthalmopathy: systematic review and metaanalysis. J Clin Endocrinol Metab 2009;94 (8) 2708- 271619491222
Link to Article[[XSLOpenURL/10.1210/jc.2009-0376]]
Evans  DGLadusans  EJRimmer  SBurnell  LDThakker  NFarndon  PA Complications of the naevoid basal cell carcinoma syndrome: results of a population based study. J Med Genet 1993;30 (6) 460- 4648326488
Link to Article[[XSLOpenURL/10.1136/jmg.30.6.460]]
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Figure 1.

Pigmented bilateral basal cell carcinoma (BCC) of the temple. A and B, Right (A) and left (B) hair-covered temples after shaving. C and D, Asymmetric gray-brown tumor with a few scales (C) and asymmetric trabecular tumor of gray-brown color and central ulceration (D) (white frames indicate field of view for dermoscopy, and scale bars indicate centimeters). E and F, Dermoscopy of the right (E) and left (F) temple BCCs reveal spoke wheel areas (boxes 1), blue-gray ovoid nests (boxes 2), arborizing vessels (box 3), and central ulceration (box 4) (original magnifications ×50 [E] and ×20 [F]).

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Figure 2.

Histopathologic analysis of the excised tumors. Nests of basaloid cells with palisading nuclei are seen in the periphery surrounded by fibromyxoid stroma and lymphocytic infiltrates. Prominent pigment particles account for the macroscopically evident hyperpigmentation of the tumors (hematoxylin-eosin, original magnification ×40).

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