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Cold Atmospheric Plasma:  A Successful Treatment of Lesions in Hailey-Hailey Disease

Georg Isbary, MD; Gregor Morfill, PhD; Julia Zimmermann, PhD; Tetsuji Shimizu, PhD; Wilhelm Stolz, MD
Arch Dermatol. 2011;147(4):388-390. doi:10.1001/archdermatol.2011.57.
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Rare diseases, such as Hailey-Hailey disease (HHD), have a common problem: There is a lack of clinical trials due to low patient numbers, and therefore clinicians can often go back to only a limited number of treatment options. Cold atmospheric plasma is an innovative new medical technique that demonstrated its beneficial use in a patient with HHD.

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Figure 1.

Right axilla. A, Before plasma treatment. B, Clinical improvement seen after 8 cold plasma treatments.

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Figure 2.

View into the plasma torch. Plasma is generated by the 6 electrodes. The torch is then held 2 cm above the area to be treated. Argon gas carries the active plasma components to the target area.

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Figure 3.

Right side of the groin. A, Appearance of the right side of the groin after 4 cold plasma treatments. B, Appearance of the right side of the groin after 11 cold plasma treatments with only residual erythema remaining.

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