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Graphic Jump Location
Various biopsy specimens are depicted showing inadequate technique and/or specimen size submitted by health care providers to our dermatopathology practice for evaluation. A-C, Superficial curettage specimen of melanoma. The arrow in A points to the area shown at higher magnification in B; C represents the accompanying melan-a stain. D, Superficial curettage specimen obtained to rule out chondrodermatitis nodularis helicis. Only the superficial papillary dermis was sampled and is present focally only. The typical architectural features of the disease cannot be evaluated, thus precluding a definitive diagnosis. E, This 2-mm punch biopsy specimen extends into the upper reticular dermis only. It was performed to rule out a folliculitis. Despite step sections through the block, a hair follicle was not noted. F, This superficial shave biopsy specimen extends into the midepidermis only, despite step sections. The intended purpose of the biopsy, to rule out basal cell carcinoma, could not be achieved by histopathologic examination. G, This shave biopsy specimen of the scalp was submitted to rule out alopecia areata. Specimens A, D, and F were obtained by board-certified dermatologists; E and G, by physician assistants. Hematoxylin-eosin was used in all specimens except panel C, for which melan-a was used; original magnifications for panels A, B, C, D, E, F, and G were ×12.5, ×200, ×200, ×50, ×50, ×25, and ×25, respectively.