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Correspondence |

Atypical Fibroxanthoma in an African American Woman

Grace E. Brown, MD; Monica M. Madray, MD; John F. Greene Jr, MD; Katherine H. Fiala, MD
Arch Dermatol. 2010;146(9):1045-1047. doi:10.1001/archdermatol.2010.238.
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Morgan  MBPurohit  CAnglin  TR Immunohistochemical distinction of cutaneous spindle cell carcinoma. Am J Dermatopathol 2008;30 (3) 228- 232
PubMed Link to Article[[XSLOpenURL/10.1097/DAD.0b013e31816de820]]
Dei Tos  APMaestro  RDoglioni  C  et al.  Ultraviolet-induced p53 mutations in atypical fibroxanthoma. Am J Pathol 1994;145 (1) 11- 17
Gohara  MA Skin cancer in skins of color. J Drugs Dermatol 2008;7 (5) 441- 445
Zanetti  RRosso  SMartinez  C  et al.  Comparison of risk patterns in carcinoma and melanoma of the skin in men: a multi-centre case-case-control study. Br J Cancer 2006;94 (5) 743- 751
Shao  LNewell  BQuintanilla  N Atypical fibroxanthoma and squamous cell carcinoma of the conjunctiva in xeroderma pigmentosum. Pediatr Dev Pathol 2007;10 (2) 149- 152
PubMed Link to Article[[XSLOpenURL/10.2350/06-06-0103.1]]
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Figure 1.

Flesh-colored papule.

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Figure 2.

Histopathologic and immunophenotypic features were consistent with the diagnosis of atypical fibroxanthoma (hematoxylin-eosin, all panels). A, Bulging nodular circumscribed tumor. B, Atypical pleomorphic cells with a few lymphocytes. C, Markedly atypical cells with foamy xanthomatous cytoplasm. D, Abnormal mitotic figure. Original magnifications ×20 (A), ×200 (B), and ×400 (C and D).

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