Editorial |

Identification of Risk Factors for Psoriatic Arthritis:  Scientific Opportunity Meets Clinical Need

Alexis Ogdie, MD; Joel M. Gelfand, MD, MSCE
Arch Dermatol. 2010;146(7):785-788. doi:10.1001/archdermatol.2010.136.
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Psoriatic arthritis (PsA) is a chronic inflammatory disease that can be progressive and may be associated with permanent joint damage and disability. Though rare in the general population, it is common in patients with psoriasis, affecting about 6% to 10% of patients with psoriasis overall and substantially more patients with more extensive skin disease (20%-40%).1,2 In most patients with PsA, the symptoms do not develop until years after the onset of cutaneous psoriasis. As a result, patients with psoriasis represent a unique opportunity to identify individuals at very high risk of developing a chronic inflammatory arthropathy (ie, PsA). To determine which patients with psoriasis are at greatest risk of developing PsA, it is essential that risk factors be identified using robust epidemiologic approaches.

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