It has been suggested that a lesion of porokeratosis results from a local or systemic change in immune function that in turn allows the development of atypical clones of keratinocytes. Useful medical modalities should therefore work by inhibiting cell growth and proliferation as well as regulating and modulating keratinocyte differentiation. Oral and topical retinoids,1,2 fluorouracil cream,3 vitamin D3 analogues,4 diclofenac gel,5 and imiquimod cream6 have all been used to treat porokeratosis. Surgical options include excision, cryotherapy,7 dermabrasion,8 and laser therapy.9 The benefits of surgical treatment are improved cosmesis and function and removal of lesions that have undergone malignant transformation. The disadvantages include scarring, pain, and lesion recurrence. For these reasons, effective alternatives to surgery are desired, particularly for benign porokeratosis. An ideal form of treatment for this benign chronic condition should be pain free, effective, safe, and nonscarring.10 Many of the traditional therapies used for PM had previously been used in our patient, without adequate success; therefore, an alternative and novel therapy was attempted.