The latest technological advance in the field of fractional lasers is demonstrated in a novel fractional device: Affirm with Multiplex technology (Cynosure, Westford, Massachusetts), a combination Nd:YAG laser emitting 1320- and 1440-nm wavelengths in sequential 3-millisecond pulses composed of 1000 microbeams per 10-mm spot. The 1440-nm wavelength exerts a resurfacing effect and acts more superficially, targeting rhytids and pigmentation. The 1320-nm wavelength targets deeper tissues, stimulating neocollagenesis and thereby improving skin laxity.
Reappearance of fractional laser–induced treatment zone erythema following a hot shower. A, Appearance of normal forearm skin prior to treatment. Appearance of treatment areas after 5 minutes (B), 30 minutes (C), 48 hours (D), and 48 hours after a hot shower (E). Arrows indicate nevi. Fluences of the corresponding wavelengths of the combination fractional laser device are provided. Although these results were obtained from a time course experiment in which forced air and direct cooling were not used, the recall phenomenon occurs in the presence or absence of cooling (data not shown).
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