We were interested to read the research letter by Bulliard et al1 published in the April 2008 issue of the Archives. Their observation of a left-sided excess of cutaneous melanoma in 5 regions of Switzerland is consistent with the results of our group's own study spanning 6 different countries, which was published in the European Journal of Cancer last year.2 Like Bulliard et al, we did not appreciate that the laterality of melanoma had been studied before, but after our study results were published, we became aware of a previously published study, based on US Surveillance Epidemiology and End Results (SEER) data (1973-1987), concluding that no substantial or consistent laterality bias existed in melanoma.3 However, the results of our own study,2 including more recent US SEER data (1998-2003), combined with the findings of Bulliard et al,1 represent data from 7 countries and suggest that the consistent observation of a left-sided excess of cutaneous melanoma is unlikely to be a chance finding. Analysis of more recent US SEER white population data4 (covering the years of incidence 2004-20055) reveals a persistently elevated overall left to right ratio of 1.09 (95% confidence interval, 1.06-1.12).
Thank you for submitting a comment on this article. It will be reviewed by JAMA Dermatology editors. You will be notified when your comment has been published. Comments should not exceed 500 words of text and 10 references.
Do not submit personal medical questions or information that could identify a specific patient, questions about a particular case, or general inquiries to an author. Only content that has not been published, posted, or submitted elsewhere should be submitted. By submitting this Comment, you and any coauthors transfer copyright to the journal if your Comment is posted.
* = Required Field
Disclosure of Any Conflicts of Interest*
Indicate all relevant conflicts of interest of each author below, including all relevant financial interests, activities, and relationships within the past 3 years including, but not limited to, employment, affiliation, grants or funding, consultancies, honoraria or payment, speakers’ bureaus, stock ownership or options, expert testimony, royalties, donation of medical equipment, or patents planned, pending, or issued. If all authors have none, check "No potential conflicts or relevant financial interests" in the box below. Please also indicate any funding received in support of this work. The information will be posted with your response.
Some tools below are only available to our subscribers or users with an online account.
Download citation file:
Web of Science® Times Cited: 5
Customize your page view by dragging & repositioning the boxes below.
More Listings atJAMACareerCenter.com >
Enter your username and email address. We'll send you a link to reset your password.
Enter your username and email address. We'll send instructions on how to reset your password to the email address we have on record.
Athens and Shibboleth are access management services that provide single sign-on to protected resources. They replace the multiple user names and passwords necessary to access subscription-based content with a single user name and password that can be entered once per session. It operates independently of a user's location or IP address. If your institution uses Athens or Shibboleth authentication, please contact your site administrator to receive your user name and password.