Scleredema, an uncommon condition with unknown pathophysiologic characteristics, is characterized by nonpitting induration of the skin with occasional erythema. Limited options are available to treat patients with scleredema diabeticorum. We report herein the effect of UV-A1 treatment (340-400 nm) in 3 patients with severe scleredema diabeticorum.
Mean (SD) durometer scores. The baseline mean durometer score was defined as 100%. The points were selected on anatomic sites where no bony structures were present directly beneath the skin. During the first visit, photographs of the measure points were taken to guarantee measurements of the same location at subsequent visits.
Mucin between thickened collagen bundles (alcian blue, original magnification ×400).
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