Correspondence |

Scleredema Diabeticorum Case Series: Successful Treatment With UV-A1

Elisabeth B. M. Kroft, MD; Elke M. G. J. de Jong
Arch Dermatol. 2008;144(7):947-948. doi:10.1001/archderm.144.7.947.
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Scleredema, an uncommon condition with unknown pathophysiologic characteristics, is characterized by nonpitting induration of the skin with occasional erythema. Limited options are available to treat patients with scleredema diabeticorum. We report herein the effect of UV-A1 treatment (340-400 nm) in 3 patients with severe scleredema diabeticorum.

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Mutzhas  MFHölzle  EHofmann  CPlewig  G A new apparatus with high radiation energy between 320-460 nm: physical description and dermatological applications. J Invest Dermatol 1981;76 (1) 42- 47
Janiga  JJWard  DHLim  HW UVA-1 as a treatment for scleredema. Photodermatol Photoimmunol Photomed 2004;20 (4) 210- 211
Eberlein-König  BVogel  MKatzer  K  et al.  Successful UVA1 phototherapy in a patient with scleredema adultorum. J Eur Acad Dermatol Venereol 2005;19 (2) 203- 204
Tuchinda  CKerr  HATaylor  CR  et al.  UVA1 phototherapy for cutaneous diseases: an experience of 92 cases in the United States. Photodermatol Photoimmunol Photomed 2006;22 (5) 247- 253
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Figure 1.

Mucin between thickened collagen bundles (alcian blue, original magnification ×400).

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Figure 2.

Mean (SD) durometer scores. The baseline mean durometer score was defined as 100%. The points were selected on anatomic sites where no bony structures were present directly beneath the skin. During the first visit, photographs of the measure points were taken to guarantee measurements of the same location at subsequent visits.

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