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Correspondence |

Granulomatous Panniculitis Associated With Sjögren Syndrome

Chethana Chandrupatla, MD; Ling Xia, MD; Erik J. Stratman, MD
Arch Dermatol. 2008;144(6):815-816. doi:10.1001/archderm.144.6.815.
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Sjögren syndrome is characterized by lymphocytic infiltrates in exocrine organs. Patients present with xerophthalmia, xerostomia, and parotid gland enlargement. Sjögren syndrome is associated with an uncommon but distinctive form of panniculitis. We present a case of a woman who developed a lobular granulomatous panniculitis associated with Sjögren syndrome.

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PubMed Link to Article[[XSLOpenURL/10.1046/j.1440-0960.2000.00428.x]]
Yamamoto  TYokoyama  AYamamoto  YMamada  A Erythema nodosum associated with Sjögren's syndrome. Br J Rheumatol 1997;36 (6) 707- 708
PubMed Link to Article[[XSLOpenURL/10.1093/rheumatology/36.6.707]]
McGovern  TWErickson  ARFitzpatrick  JE Sjögren's syndrome plasma cell panniculitis and hidradenitis. J Cutan Pathol 1996;23 (2) 170- 174
PubMed Link to Article[[XSLOpenURL/10.1111/cup.1996.23.issue-2]]
Ueki  HInagaki  YHamasaki  YOno  M Dermatological manifestations of Sjögren's syndrome [in German]. Hautarzt 1991;42 (12) 741- 747
Francis  MLRanatunga  SM Sjögren's syndrome. eMedicine May4 2006;http://www.emedicine.com/med/topic2136.htm. Accessed April 27, 2007
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Figure 1.

Patient's left forearm. A, Erythematous indurated plaque 7 days after intralesional steroid injection. B, Complete resolution after 2 months of treatment with colchicine.

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Figure 2.

Histologic examination with hematoxylin-eosin reveals inflammation in the subcutaneous fat (larger photograph, original magnification ×4) multinucleated giant cells and lymphohistiocytic infiltrate (inset, original magnification ×20).

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