We're unable to sign you in at this time. Please try again in a few minutes.
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Correspondence |

Contact Dermatitis to Pentylene Glycol in a Prescription Cream for Atopic Dermatitis: Case Report

Antoine Amado, MD; James S. Taylor, MD; Debora A. Murray, LPN; Jeffrey S. Reynolds, BS
Arch Dermatol. 2008;144(6):810-812. doi:10.1001/archderm.144.6.810.
Text Size: A A A
Published online


According to the package insert, MimyX Cream (Stiefel Laboratories Inc, Coral Gables, Florida) is a “fragrance-free, preservative-free, water-based emulsion formulated for the management and relief of the burning and itching experienced with various types of dermatoses, including atopic dermatitis, allergic contact dermatitis and radiation dermatitis.”1 The MimyX Cream package label lists the following ingredients: purified water, olive oil, glycerin, pentylene glycol (PTG), palm glycerides, vegetable oil, hydrogenated lecithin, squalane, betaine, palmitamide monoethanolamine (PEA), sarcosine, acetamide monoethanolamine, hydroxyethyl cellulose, sodium carbomer, carbomer, and xanthan gum.1 The PEA is an endogenous bioactive fatty acid that is deficient in atopic skin and is reported to be replenished by MimyX Cream.2 The cream is also said to restore the disrupted skin barrier characteristic of atopic dermatitis.2

Figures in this Article

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

First Page Preview

View Large
First page PDF preview


Place holder to copy figure label and caption

Positive patch test results to MimyX Cream (Stiefel Laboratories, Coral Gables, Florida); a different proprietary blend (PB) (10%, 20%, and 30%) containing some MimyX Cream ingredients, including pentylene glycol (PTG); and PTG alone, 5% and 10%.

Graphic Jump Location




Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.


Some tools below are only available to our subscribers or users with an online account.

6 Citations

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

Related Content

Customize your page view by dragging & repositioning the boxes below.

Articles Related By Topic
Related Collections
PubMed Articles