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Correspondence |

A Complication of Mesotherapy: Noninfectious Granulomatous Panniculitis

Mark D. P. Davis, MD; Tina I. Wright, MD; James M. Shehan, MD
Arch Dermatol. 2008;144(6):808-809. doi:10.1001/archderm.144.6.808.
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Mesotherapy can be associated with noninfectious granulomatous panniculitis and consequent scarring.

Rotunda  AMKolodney  MS Mesotherapy and phosphatidylcholine injections: historical clarification and review. Dermatol Surg 2006;32 (4) 465- 480
PubMed Link to Article[[XSLOpenURL/10.1111/dsu.2006.32.issue-4]]
Lee  DPChang  SE Subcutaneous nodules showing fat necrosis owing to mesotherapy. Dermatol Surg 2005;31 (2) 250- 251
PubMed
Sanchez  JESanchez  SSanchez  JLVazquez-Botet  MSangueza  P Severe lobular panniculitis due to mesotherapy. Car J Dermatol 2006;3 (3) 47- 50
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Figure 2.

Hematoxylin-eosin–stained biopsy specimens showing dermal pannicular abscess and granulomatous inflammation in the panniculus (larger photograph; original magnification ×2) and granulomatous inflammation (inset; original magnification ×10).

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Figure 1.

Numerous violaceous nodules, with and without crusted erosions, and hyperpigmented macules at injection sites. A, Left buttock; B, right buttock; C, left thigh, left lateral and superior aspects of the knee, right medial aspect of the knee, and right medial aspect of the lower leg; and D, right thigh, right lateral and superior aspects of the knee, left medial aspect of the knee, and left medial aspect of the lower leg.

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