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The Treatment of Diffuse Dermal Angiomatosis of the Breast With Reduction Mammaplasty

Mark T. Villa, MD; Lucile E. White, MD; Vesna Petronic-Rosic, MD, MSc; David H. Song, MD
Arch Dermatol. 2008;144(5):693-694. doi:10.1001/archderm.144.5.693.
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Diffuse dermal angiomatosis (DDA) is a rare, cutaneous vascular disorder described in 1994.1 Initially, it was thought to be a variant of the reactive angioendotheliomatoses in which endothelial cells proliferate within dermal capillaries. In contrast, the endothelial cell proliferation of DDA occurs extravascularly within the dermal stroma. The condition is characterized clinically by painful, poorly circumscribed, erythematous plaques that often exhibit central ulceration.23

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Figure 1.

Surgical treatment of diffuse dermal angiomatosis of the breast. A, Preoperatively, the patient presented with the ulcerating lesions characteristic of diffuse dermal angiomatosis on her breasts. B, Approximately 4 months after her bilateral reduction mammaplasty, the patient had an acceptable cosmetic result and no recurrence of the condition.

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Figure 2.

Histologic study of diffuse dermal angiomatosis demonstrating a diffuse endothelial proliferation within the dermis forming vascular spaces (hematoxylin-eosin, original magnification ×200).

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