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Correspondence |

Necrobiosis Lipoidica in Monozygotic Twins

Iakov Shimanovich, MD; Hanieh Erdmann, MD; Jürgen Grabbe, MD; Detlef Zillikens, MD; Christian Rose, MD
Arch Dermatol. 2008;144(1):119-120. doi:10.1001/archdermatol.2007.26.
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Necrobiosis lipoidica (NL) is a chronic granulomatous dermatitis typically localized to the shins and associated with diabetes mellitus (DM). While various authorities consider NL to be primarily a disease of collagen degeneration or a vasculopathy, its exact etiology and pathogenesis remain unknown.

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Lesions of necrobiosis lipoidica on the shins of monozygotic twins with type 2 diabetes mellitus. A, The original patient; B, her twin sister.

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Necrobiosis lipoidica in monozygotic twins. Arch Dermatol 2008;144(1):119-20.