0
We're unable to sign you in at this time. Please try again in a few minutes.
Retry
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
Retry
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Correspondence |

Necrobiosis Lipoidica in Monozygotic Twins

Iakov Shimanovich, MD; Hanieh Erdmann, MD; Jürgen Grabbe, MD; Detlef Zillikens, MD; Christian Rose, MD
Arch Dermatol. 2008;144(1):119-120. doi:10.1001/archdermatol.2007.26.
Text Size: A A A
Published online

Extract

Necrobiosis lipoidica (NL) is a chronic granulomatous dermatitis typically localized to the shins and associated with diabetes mellitus (DM). While various authorities consider NL to be primarily a disease of collagen degeneration or a vasculopathy, its exact etiology and pathogenesis remain unknown.

Borssén  BBergenheim  TLithner  F The epidemiology of foot lesions in diabetic patients aged 15-50 years. Diabet Med 1990;7 (5) 438- 444
PubMed Link to Article[[XSLOpenURL/10.1111/dme.1990.7.issue-5]]
O’Toole  EAKennedy  UNolan  JJYoung  MMRogers  SBarnes  L Necrobiosis lipoidica: only a minority of patients have diabetes mellitus. Br J Dermatol 1999;140 (2) 283- 286
PubMed Link to Article[[XSLOpenURL/10.1046/j.1365-2133.1999.02663.x]]
Medici  FHawa  MIanari  APyke  DALeslie  RD Concordance rate for type II diabetes mellitus in monozygotic twins: actuarial analysis. Diabetologia 1999;42 (2) 146- 150
PubMed Link to Article[[XSLOpenURL/10.1007/s001250051132]]
Seviour  PWElkeles  RS Necrobiosis lipoidica in two diabetic sisters. Clin Exp Dermatol 1985;10 (2) 159- 161
PubMed Link to Article[[XSLOpenURL/10.1111/ced.1985.10.issue-2]]
Ho  KKO’Loughlin  SPowell  FC Familial non-diabetic necrobiosis lipoidica. Australas J Dermatol 1992;33 (1) 31- 34
PubMed Link to Article[[XSLOpenURL/10.1111/ajd.1992.33.issue-1]]
Soler  NGMcConnachie  PR HLA antigens and necrobiosis lipoidica diabeticorum—a comparison between insulin-dependent diabetes with and without necrobiosis. Postgrad Med J 1983;59 (698) 759- 762
PubMed Link to Article[[XSLOpenURL/10.1136/pgmj.59.698.759]]
Figures in this Article

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

First Page Preview

View Large
First page PDF preview

Figures

Place holder to copy figure label and caption
Figure.

Lesions of necrobiosis lipoidica on the shins of monozygotic twins with type 2 diabetes mellitus. A, The original patient; B, her twin sister.

Graphic Jump Location

Tables

References

Correspondence

CME
Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.

Multimedia

Some tools below are only available to our subscribers or users with an online account.

46 Views
3 Citations
×

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

Related Content

Customize your page view by dragging & repositioning the boxes below.

Articles Related By Topic
Related Collections
PubMed Articles
Necrobiosis lipoidica in monozygotic twins. Arch Dermatol 2008;144(1):119-20.
Jobs
brightcove.createExperiences();