Author Contributions: Dr Ziemer had full access to all the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis. Drs Ziemer and Wiesend contributed equally to this work. Study concept and design: Ziemer and Mockenhaupt. Acquisition of data: Wiesend, Vetter, Weiss, Blaschke, and Mockenhaupt. Analysis and interpretation of data: Ziemer, Wiesend, Vetter, Blaschke, Norgauer, and Mockenhaupt. Drafting of the manuscript: Ziemer, Wiesend, Weiss, and Blaschke. Critical revision of the manuscript for important intellectual content: Ziemer, Wiesend, Vetter, Blaschke, Norgauer, and Mockenhaupt. Obtained funding: Mockenhaupt. Administrative, technical, and material support: Ziemer, Wiesend, Weiss, Norgauer, and Mockenhaupt. Study supervision: Blaschke and Mockenhaupt.