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Correspondence |

Hypereosinophilic Syndrome With Peripheral Circulatory Insufficiency and Cutaneous Microthrombi

Takahiro Hamada, MD; Yoko Kimura, MD; Shinsuke Hayashi, MD; Takekuni Nakama, MD; Takashi Hashimoto, MD
Arch Dermatol. 2007;143(6):799-816. doi:10.1001/archderm.143.6.812.
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Chusid  MJDale  DCWest  BCWolff  SM The hypereosinophilic syndrome: analysis of fourteen cases with review of the literature. Medicine (Baltimore) 1975;541- 27
PubMed Link to Article[[XSLOpenURL/10.1097/00005792-197501000-00001]]
Barna  MKemeny  LDobozy  A Skin lesions as the only manifestation of the hypereosinophilic syndrome. Br J Dermatol 1997;136646- 647
PubMed Link to Article[[XSLOpenURL/10.1111/j.1365-2133.1997.tb02176.x]]
Weller  PFBubley  GJ The idiopathic hypereosinophilic syndrome. Blood 1994;832759- 2779
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PubMed Link to Article[[XSLOpenURL/10.1046/j.1365-2133.2003.05309.x]]
Liapis  HHo  AKBrown  DMindel  GGleich  G Thrombotic microangiopathy associated with the hypereosinophilic syndrome. Kidney Int 2005;671806- 1811
PubMed Link to Article[[XSLOpenURL/10.1111/kid.2005.67.issue-5]]
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Figure 1.

Clinical features of the patient. A, Erythematous indurated patches and Raynaud phenomenon on the right hand. B, Features were improved with mild purpura on the fingertips after administration of prednisolone.

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Figure 2.

Light microscopy evaluation of the palm skin revealed prominent eosinophilic infiltration around the blood vessel and microthrombi without vasculitis (hematoxylin-eosin, original magnification ×200).

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