0
We're unable to sign you in at this time. Please try again in a few minutes.
Retry
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
Retry
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Correspondence |

Involution: The Natural Evolution of Pigmented Spitz and Reed Nevi?

Giuseppe Argenziano, MD; Iris Zalaudek, MD; Gerardo Ferrara, MD; Antonio Lorenzoni, MD; H. Peter Soyer, MD
Arch Dermatol. 2007;143(4):543-551. doi:10.1001/archderm.143.4.549.
Text Size: A A A
Published online

Extract

The natural history of melanocytic nevi is poorly understood owing to the lack of follow-up studies investigating their long-term evolution. Current epidemiologic data report that the number of pigmented Spitz and Reed nevi (PSRN) peaks during the first or second decades of life, while they are rarely seen by the seventh to ninth decades.1 An explanation might be their gradual involution, but this assumption has still to be proven. We report herein 2 cases of pigmented lesions with typical clinical and dermoscopic features of PSRN that showed gradual involution at the follow-up examinations.

Figures in this Article

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

First Page Preview

View Large
First page PDF preview

Figures

Place holder to copy figure label and caption
Figure 1.

Evolution of a small pigmented lesion over 3 years. A, Dermoscopically, the lesion is characterized by a starburst pattern with pigmented streaks regularly distributed at the periphery. B, After 3 years, an almost complete involution of the lesions has occurred, with only remnants of light-brown pigmentation visible.

Graphic Jump Location
Place holder to copy figure label and caption
Figure 2.

Evolution of a symmetric pigmented papule of the left lower leg over 6 months. A, Clinical view. B, Dermoscopically, striking brown to black globules of varying size are visible. C, After 1 month, a substantial decrease in the number and size of brown globules is apparent. D, After 6 months, the globules are not discernible anymore, and only remnants of light-brown to gray pigmentation are still visible.

Graphic Jump Location

Tables

References

Correspondence

CME
Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.

Multimedia

Some tools below are only available to our subscribers or users with an online account.

208 Views
0 Citations
×

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

Related Content

Customize your page view by dragging & repositioning the boxes below.

Articles Related By Topic
Related Collections
PubMed Articles
Jobs
brightcove.createExperiences();