In an attempt to coin the correct denomination, a critical review of the literature was performed to conclude 2 differential diagnoses: the rare variant of verrucous-hyperkeratotic melanoma and follicular melanoma (FM). Verrucous-hyperkeratotic melanoma was described in 1982 by Kuehnl-Petzoldt et al3 as a variant of melanoma that might often be diagnosed, both clinically and histopathologically, as benign verrucoid lesions, especially seborrheic keratosis. It is usually observed in the extremities of women and characterized by marked verrucous hyperplasia and hyperkeratosis of the epidermis. Histopathologically, these authors described, as additional typical features, the proliferation of neoplastic cells mostly at the dermoepidermal interface rather than in the upper reaches of the epidermis and the absence of nodule formation. The prognosis of verrucous-hyperkeratotic melanoma did not differ from that of nonverrucous melanomas matched for sex, anatomic site, and thickness of the neoplasm. In 1993, Blessing et al4 reported a series of 20 cases of verrucous-nevoid melanoma, and they found them more often on the back and limbs of male patients with a mean age of 57 years. Clinical diagnosis of benign lesions (warty nevi, papillomas, seborrheic keratosis, and cysts) had been made in more than 50% of the cases. Histopathologically, these lesions were characterized by a spectrum of nevoid features, combined with marked epidermal hyperplasia, elongation of rete ridges, and overlying hyperkeratosis. At the same time, lesions showed typical melanoma findings, such as intraepidermal invasion and pleomorphism. They emphasize that histopathological classification may be very difficult, since more than 50% of their cases were initially labeled unclassifiable and 10% were histopathologically diagnosed as benign lesions. In these 2 retrospective clinicopathological studies, the contradictory epidemiologic data that were found probably reflects an insufficient number of cases because this is not a common type of melanoma. To date, only extremely rare additional cases have been reported, such as melanomas associated with pseudocarcinomatous hyperplasia9,10 or other entities that combine biphenotypic characteristics in the same neoplasm.11- 13 The histopathological appearance of our case obviously differs from verrucous-hyperkeratotic melanoma, since the lack of epidermal hyperplasia and hyperkeratosis is evident.