0
We're unable to sign you in at this time. Please try again in a few minutes.
Retry
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
Retry
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Editorial |

Skin Microecology The Old and the New

Guy F. Webster, MD, PhD
Arch Dermatol. 2007;143(1):105-106. doi:10.1001/archderm.143.1.105.
Text Size: A A A
Published online

Extract

Interest in the ecology of skin bacteria and the skin as a habitat has waxed and waned over the past 30 or so years. The past few years have been a particularly active time as were the 1970s. Thirty years ago, a wealth of research demonstrated that different regions of the skin have distinct and reproducible bacterial populations that are determined by the cutaneous anatomy.1

Three major factors were shown to determine the skin habitats: moisture, lipids, and the ability to maintain a reduced environment. Sebum is the most potent determinant of skin flora. Prior to the pubertal surge in testosterone, sebaceous glands are inactive and the skin microflora is greatly reduced. After puberty, in areas where sebum is plentiful, such as the head and upper trunk, there is a stable population of lipophilic organisms numbering in the tens of millions. The anaerobic propionibacteria dominate the region by virtue of an extracellular lipase that liberates glycerol from sebaceous triglycerides, which is then used as a carbon source. The fatty acids are unused by the bacteria and remain in sebum. The sebaceous gland provides a second ecological determinant, an enclosed relatively anoxic crypt where facultative anaerobes like propionibacteria can survive in the depths and lipophilic aerobes such as yeast of the Malassezia genus occupy the acroinfundibulum.13

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

First Page Preview

View Large
First page PDF preview

Figures

Tables

References

Correspondence

CME
Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.

Multimedia

Some tools below are only available to our subscribers or users with an online account.

83 Views
2 Citations
×

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

Related Content

Customize your page view by dragging & repositioning the boxes below.

See Also...
Articles Related By Topic
Related Collections
PubMed Articles
Jobs
JAMAevidence.com

The Rational Clinical Examination: Evidence-Based Clinical Diagnosis
Evidence to Support the Update

The Rational Clinical Examination: Evidence-Based Clinical Diagnosis
Evidence Summary and Review 1

brightcove.createExperiences();