Cutaneous spicules are a characteristic paraneoplastic sign for multiple myeloma.1- 4 These spicules are composed of the monoclonal protein present in the patient's serum.4 Cutaneous spicules of the scalp have been reported, but to the best of our knowledge have not been biochemically investigated.2 Herein, we describe a patient with multiple myeloma who was seen with cutaneous spicules on the nose and hair casts. Biochemical analysis demonstrated the presence of the patient's serum monoclonal protein in the cutaneous spicules and hair casts. We propose that hair casts should be recognized as a characteristic finding along with cutaneous spicules in patients with multiple myeloma.
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Cutaneous spicules of the nose.
Hair casts on eyelid.
Hair casts on scalp hair.
In a horizontal section of a hair cast, amorphous eosinophilic material is seen between keratinocytes in the outer root sheath (hematoxylin-eosin, original magnification ×200).
Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature
Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal
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