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Correspondence |

The Cutaneous Predilection of Disseminated Cryptococcal Infection in Organ Transplant Recipients

Kathleen Moe, MD; Angela J. Lotsikas-Baggili, MD; Agnieszka Kupiec-Banasikowska, MD; Catharine Lisa Kauffman, MD
Arch Dermatol. 2005;141(7):913-914. doi:10.1001/archderm.141.7.913.
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Immunocompromised individuals constitute the majority of patients diagnosed as having cryptococcosis1; however, with improving antiretroviral agents for patients with AIDS, organ transplant recipients are at the highest risk of acquiring the infection. A recent review studied the incidence of Cryptococcus neoformans in transplant recipients and found that the mean incidence of infection was 2.8 per 100 transplant recipients, while the overall death rate was 72 (42%) of 172 recipients.2

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Figure 2.

Capsular polysaccharides of Cryptococcus neoformans stain intense red with periodic acid–Schiff and mucicarmine (original magnification ×400).

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Figure 1.

Hematoxylin-eosin staining reveals numerous round fungi (arrowhead) with a thick gelatinous capsule (original magnification ×400).

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