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Possible Involvement of Mycoplasma fermentans in the Development of Nonsexually Acquired Genital Ulceration (Lipschütz Ulcers) in 3 Young Female Patients

Chiho Horie, MD1; Yoko Kano, MD, PhD1; Takayo Mitomo, MD1; Tetsuo Shiohara, MD, PhD1
[+] Author Affiliations
1Department of Dermatology, Kyorin University School of Medicine, Tokyo, Japan
JAMA Dermatol. 2015;151(12):1388-1389. doi:10.1001/jamadermatol.2015.2061.
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This case report describes the possible involvement of Mycoplasma fermentans in the development of nonsexually acquired genital ulceration (Lipschütz ulcers) in 3 young female patients.

Nonsexually acquired genital ulceration (NSAGU), also known as Lipschütz ulcers, is clinically characterized by acute painful genital ulcerations in young women and girls.13 Although various causative pathogens have been documented in the development of NSAGU, the involvement of Mycoplasma fermentans has not previously been proven. We report herein the cases of 3 consecutive patients with NSAGU associated with a recent M fermentans infection. We describe 1 of these cases in detail.

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Clinical Image of Acute Genital Ulcer in Case 1

A necrotic ulcer overlying adherent gray-brown eschar on the edematous major labium.

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