0
We're unable to sign you in at this time. Please try again in a few minutes.
Retry
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
Retry
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Observation |

Disseminated Cutaneous Cytomegalovirus Infection Following Total Body Electron Beam Irradiation for Mycosis Fungoides

Julie K. Kim, MD1; Adeel Ahmad, MD2; M. Angelica Selim, MD3,4; Elise A. Olsen, MD3,5; Adela R. Cardones, MD3,6
[+] Author Affiliations
1Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas
2Eastern Pathology and Dermatology Associates and Surgery Center, Beckley, West Virginia
3Department of Dermatology, Duke University Medical Center, Durham, North Carolina
4Department of Pathology, Duke University Medical Center, Durham, North Carolina
5Department of Medicine, Duke University Medical Center, Durham, North Carolina
6Durham VA Medical Center, Durham, North Carolina
JAMA Dermatol. 2015;151(12):1380-1381. doi:10.1001/jamadermatol.2015.2233.
Text Size: A A A
Published online

Extract

This case report describes the occurrence of disseminated cutaneous cytomegalovirus infection in an immunocompromised patient following total body electron beam irradiation for mycosis fungoides.

Cutaneous cytomegalovirus (CMV) infections are rare and are often associated with poor prognosis from an underlying malignant condition or immunosuppression.1,2 We report a unique case of disseminated cutaneous CMV infection and CMV viremia following total body electron beam (TBEB) irradiation.

Figures in this Article

First Page Preview

View Large
First page PDF preview

Figures

Place holder to copy figure label and caption
Figure 1.
Clinical Presentation of Cutaneous Cytomegalovirus Infection

Shallow, punched-out, oval ulcerations are seen scattered diffusely on the trunk and extremities.

Graphic Jump Location
Place holder to copy figure label and caption
Figure 2.
Pathologic Findings From Cutaneous Cytomegalovirus (CMV) Ulcer Specimens

In the primary image, scattered endothelial cells in small dermal vessels demonstrate large eosinophilic intranuclear inclusions surrounded by a clear halo (arrowhead) (hematoxylin-eosin, original magnification ×40). The inset highlights several endothelial cells and fibroblasts (CMV immunohistochemical stain, original magnification ×40).

Graphic Jump Location

Tables

References

Correspondence

CME
Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.

Multimedia

Some tools below are only available to our subscribers or users with an online account.

410 Views
0 Citations
×

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

Related Content

Customize your page view by dragging & repositioning the boxes below.

Articles Related By Topic
Related Collections
Jobs
JAMAevidence.com

Care at the Close of Life: Evidence and Experience
What Is the Diagnosis?

The Rational Clinical Examination: Evidence-Based Clinical Diagnosis
Paracentesis

brightcove.createExperiences();