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Primary Cutaneous Trichosporonosis Responsive to Voriconazole

Neetu Bhari, MD1; Immaculata Xess, MD2; Mragnayani Pandey, MSc2; Sudheer Arava, MD3; M. Ramam, MD1
[+] Author Affiliations
1Department of Dermatology, All India Institute of Medical Sciences, New Delhi, India
2Department of Microbiology, All India Institute of Medical Sciences, New Delhi, India
3Department of Pathology, All India Institute of Medical Sciences, New Delhi, India
JAMA Dermatol. 2015;151(10):1139-1141. doi:10.1001/jamadermatol.2015.1354.
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Primary cutaneous trichosporonosis in immunocompetent individuals is very rare.

Article InformationCorresponding Author: M. Ramam, MD, Department of Dermatology, All India Institute of Medical Sciences, New Delhi, India (mramam@hotmail.com).

Published Online: June 10, 2015. doi:10.1001/jamadermatol.2015.1354.

Conflict of Interest Disclosures: None reported.

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Figure 1.
Erythematous Crusted Plaque Over Suprapubic Area

A, Well-defined erythematous plaque of 7 × 8 cm over the suprapubic area before treatment. B, Complete resolution of the plaque with residual postinflammatory hyperpigmentation after 6 months of treatment.

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Figure 2.
Biopsy Specimens and Culture Showing Trichosporon fungus

A, Potassium hydroxide preparation of the skin tissue specimen showing multiple budding yeast cells and hyaline hyphae (original magnification ×400). B, Periodic acid–Schiff staining shows mixed granulomatous inflammatory infiltrate of giant cells, lymphocytes, and histiocytes admixed with neutrophils and eosinophils along with fungal spores and septate hyphae (original magnification ×200). C, Culture plate showing dried Trichosporon colonies.

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