Parthenium hysterophorus can produce a spectrum of clinical patterns. The dermatitis usually presents as itchy, erythematous, papules and plaques on exposed areas of the body like the face, including upper eyelids, side of neck, the “V” of the upper chest, flexures of the forearms, and cubital and popliteal fossae. Parthenium dermatitis commonly begins as an airborne contact dermatitis pattern. Other patterns include chronic actinic dermatitislike, seborrheic dermatitis, prurigo nodularislike, photosensitive lichenoid eruption, and hands-and-feet dermatitis patterns.2 Repeated exacerbations are common due to continued exposure and seasonal variation. In untreated cases, it may gradually spread and eventually progress to erythroderma over variable periods of time. Patch testing helps to determine the cause of the contact dermatitis.