Purse-string suture is a wound closure technique often used for complete or partial closure of circular postoperative defects in cutaneous surgery. Proponents claim this technique reduces scar area, expedites healing, enhances homeostasis, and improves aesthetic outcome. In this prospective, randomized, blinded clinical trial, Joo et al demonstrate that purse-string closure results in cosmetic outcomes, scar sizes, and pain levels similar to those of second-intention would healing for circular or oval wounds on the trunk or extremities. Healing time might be faster with purse-string, and scar relief at 3 months might be better with second-intention healing. A larger clinical trial might clarify these trends.