Accepted for Publication: December 11, 2014.
Published Online: March 4, 2015. doi:10.1001/jamadermatol.2014.5460.
Study concept and design: Lin.
Acquisition of data: Lin.
Analysis, and interpretation of data: Lin, Huang.
Drafting of the manuscript: Lin, Huang.
Critical revision of the manuscript for important intellectual content: Lin, Hui, See, Yang.
Statistical analysis: See, C.-J. Chang.
Obtained funding: Lin.
Administrative, technical, or material support: Lin, Y.-C. Chang, Hui, Yang.
Study supervision: Lin.
Conflict of Interest Disclosures: None reported.
Funding/Support: This study was supported by grant CMRPG2A0191-2 from Chang Gung Memorial Hospital at Keelung, Taiwan (Dr Lin).
Role of the Funder/Sponsor: The funding source had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication.
Trial Registration: Clinicaltrials.gov Identifier: NCT01445886.
Additional Contributions: We thank Shu-Tuan Chiang, MSc, Chuang Song-Zong Pharmaceutical Co, Ltd, for the preparation of the study medication and Hsiao-Jung Tseng, MS, Biostatistical Center for Clinical Research (supported by grant CLRPG340599 from Chang Gung Memorial Hospital at Linkou) and Louis Tuan, MBA, Contract Research Organization Service Division, Formosa Biomedical Technology Corp, for statistical analysis of the clinical data. Chuang Song-Zong Pharmaceutical Co, Ltd, was compensated for producing the drugs used in the study. Ms Tseng and Mr Tuan were not compensated for their contributions.